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Abstract

 

Results of autologous hematopoietic stem cell transplantation in Kaunas – international telemedicine project.

 

Domas Vaitiekus, Vilma Svetickienė, Martyna Beitnerienė, Milda Rudžianskienė, Rolandas Gerbutavičius, Elona Juozaitytė.

The Hospital of Lithuanian University of Health Sciences Kauno klinikos, Oncology and hematology department.

Aim: To present The Hospital of Lithuanian University of Health Sciences Kauno klinikos, Oncology and hematology department results of HSCT programs incorporating telemedicine project.

Methods: Retrospective analysis of 86 autologous HSCT performed for the period of 2015.07-2019.01. Patient’s characteristics, transplantation period data and survival data analyzed.

Results: Telemedicine project was started under supervision of experienced director with protocols in place 2015 August. During project flowkey elements for successful telemedicine project were identified:

Personnel Training in a JACIE accreditated HSCT center and  selection of local experienced hematologists Establishment of core facilities; Site visit to the facilities;

HSCT results: Total number of transplants 86. Sex distribution: Male 48% Female 52%. Number of HSCT distribution according diseases: Multiple Myeloma 78, Lymphoma 5, testicular cancer 3. Treatment related mortality (TRM) in one hundred days (100d)- 1,16%. Multiple myeloma OS 3,5y - 90,7%

Conclusion: This innovative model of spreading of knowledge (know-how) and experience in the field of HSCT can serve as excellent example of future cellular therapies cooperation projects.  Telemedicine project help to improve learning curve and avoid failures with many years experience and result are comparable with centers that are working for many decades.

 

Biography

 

Lithuanian University of Health Sciences

Head of hematopoietic stem cell transplantation sector at the Hospital of Lithuanian University of Health Sciences, Oncology and Hematology department

 

DATE OF BIRTH - 16th July 1985

From 2018 September - Coordinator for cellular therapies implementation at the Hospital of Lithuanian University of Health Sciences

From 2018 August

Head of hematopoietic stem cell transplantation sector at the Hospital of Lithuanian University of Health Sciences, Oncology and Hematology

2018 Mar. - 2018 May

Fellowship at Leipzig University Hospital Hematology-Oncology Department. Practice in the field of bone marrow transplantation, treatment and stem cell research. Germany

From 2017 April.

Hematologist at the Hospital of Lithuanian University of Health Sciences, Oncology and Hematology department, Eiveniu str. 2 Kaunas LT - 50009, Lithuania

2016 Sep. -2020 Sep.

The Lithuanian University of Health Sciences. PhD studies. Evaluation of genetical factors of doxorubicin cardiotoxicity in breast cancer patients.

2015 Oct -2017 Mar

Resident of Hematology at the Hospital of Lithuanian University of Health Sciences, Oncology and Hematology department, Eiveniu str. 2, Kaunas LT-50009, Lithuania

From 2014 August starting

Medical Oncologist at the Hospital of Lithuanian University of Health Sciences, Oncology and Hematology department, Eiveniu str. 2, Kaunas LT-50009, Lithuania

2010. Aug. – 2014 Aug.

Resident of Medical Oncology at the Hospital of Lithuanian University of Health Sciences, Oncology and Hematology department, Eiveniu str. 2, Kaunas LT-50009, Lithuania.

2012 Aug.-2013 Feb.

Fellowship at Leipzig University Hospital Hematology-Oncology Department. Practice in the field of bone marrow transplantation, sarcoma treatment and stem cell research. Germany

2014 Jan – 2014 Feb

Fellowship at Manchester The Christie NHS Foundation Trust Hospital. Practice in the field of bone marrow transplantation, sarcoma treatment, Germ-cell cancers. United Kingdom.

EDUCATION

1992 - 2004

Kaunas „Azuolas“ Gymnasium

2004 - 2010

Medicine master degree. Kaunas University of Medicine,

BOARD CERTIFICATION

2010

Doctor of Medicine,

2014

Medical Oncologist

2017

Hematologist

PROFESSIONAL QUALIFICATIONS

Member of European Society of Medical Oncology

Member of EBMT

Member of Lithuanian Society of Medical Oncology

Participant of ESMO Baltic-Nordic Congress, Copenhagen 2011.

Participant of Baltic States Medical Oncology Association Congress, Vilnius 2011

Participant of Baltic States Medical Oncology Association Congress, Riga 2012

Participant of ESMO 2012 congress. Vienna.

Participant of ESMO preceptorship in gastric cancer. Berlin 2012. (personal expenses)

Participant of workshop for breast imaging and biopsy. Leipzig 2012.

Participant of EURORIT forum of oncology. Zagreb 2013

ESMO Northern Europe and Baltic Meeting. Copenhagen 2014.

Prostate cancer debate. Vienna 2015.

Clinical unit visit. Cremona Italy 2015.

EBMT. Istanbul, Turkey 2015.

ESMO GI 2015 Barcelona, Spain.

ESMO GIST and Sarcoma. Milan. Italy 2016; 2018.

ESH. Copenhagen. Denmark 2016.

Melanoma meeting (speaker), Slovene Medical Association, Section for Clinical Oncology, Ljubljana, Slovenia 2016.

Cardio-oncology society meeting. Poster presentation. Tel-Aviv. Israel. 2017

ESMO 2017, Madrid, Spain.

ESMO lymphoma preceptorship 2017, Lugano, Switzerland (ESMO grant).

PROFESSIONAL INTERESTS

High dose chemotherapy with stem cell support. Cellular therapies. Cardiotoxicity. Sarcoma treatment. Cancer related anemia. Pharmacogenetics.

CLINICAL TRAIS

GMP certificate 2013 06 06 Kaunas/Biomapas 2013 07 till 2015 07 II phase clinical trial for mCRPC treatment (SI) 2014 09 till now III phase clinical trial BROCADE 3 (SI) 2016 03 till now MK-3475-062 (SI) 2016 05 HALO -301 (SI)

LANGUAGES

Lithuanian native. English – fluent. German – proficient. Russian – fluent. Polish- proficient. Spanish – basic knowledge.